Assessment of Prevalence of Asymptomatic Bacteriuria and Antibiotic susceptibility and its Risk factors in pregnant women living in Sabzevar City from 2014 to 2015

Document Type : Original Article

Authors

1 Physician, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

2 Assistant Professor, Department of Obstetrics & Gynecology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

3 Assistant Professor, Department of Anesthesiology, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran.

Abstract

Introduction: Asymptomatic bacteriuria is a common problem during pregnancy. Delayed diagnosis and treatment may end up in harmful events for both mother and fetus. Physiological changes of urinary system during pregnancy facilitate the growth of microorganisms and cause this infection. This study was performed with aim to evaluate the prevalence of asymptomatic bacteriuria and determine the antibiotic susceptibility and its risk factors in pregnant women.
Methods: This cross-sectional study was performed on 220 pregnant women referred to Shahidan Mobini Hospital in Sabzevar in 2014-2015. Sterile urine sample of pregnant women was analyzed in terms of Full urine test and culture. Antibiogram of isolated bacteria was done with colony count greater than 100000 by Bauer-Kirby Disk Diffusion. Individual characteristics of the subjects were recorded in the checklist. Data were analyzed by SPSS software (version 19) and Chi-square test. P<0.05 was considered significant.
Results: In this study which was performed on 220 pregnant women, 7% of pregnant women had asymptomatic bacteriuria. Significant relationship was found between asymptomatic bacteriuria and education level (p<0.001), socioeconomic status (p=0.002), regional living area (p=0.004), history of previous urinary tract infection (p<0.001), and history of renal complications (p=0.028). However, no significant relationship was observed between asymptomatic bacteriuria and mode of last delivery, number of pregnancies and systemic underlying diseases (P>0.05). Most common isolated organisms were Escherichia coli and staphylococcus ureus. Antibiogram results showed that cotrimoxasol, nitroforantoin, ciproflouxasin and nalidixic acide are appropriate antibiotics for treatment of patients.
Conclusion: Asymptomatic bacteriuria has favorable prevalence in Sabzevar city. In the screening of this situation, considering individual and social characteristics seems to be necessary.

Keywords

References

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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 20, Issue 11
January 2018
Pages 15-21

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