بررسی تأثیر کپسول سنبل‌الطیب بر شدت پس‌درد زایمان: یک کارآزمایی بالینی تصادفی شده

نوع مقاله : اصیل پژوهشی

نویسندگان

1 کارشناس ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 کارشناس ارشد مامایی، گروه مامایی، واحد کرج، دانشگاه آزاد اسلامی، کرج، ایران.

3 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

4 کارشناس ارشد سلامت و رفاه اجتماعی، مرکز تحقیقات عوامل اجتماعی مؤثر بر سلامت، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

5 استاد گروه مامایی و بهداشت باروری، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

10.22038/ijogi.2025.83629.6243

چکیده

مقدمه: پس­ درد زایمان، درد ناشی از انقباضات متناوب رحمی بعد از خروج جفت و پرده­ ها است. به‌دلیل اثرات مضر داروهای شیمیایی، مادران به استفاده از داروهای گیاهی روی آورده‌اند. مطالعه حاضر با هدف بررسی تأثیر کپسول حاوی گیاه سنبل­ الطیب بر شدت پس­ درد­های زایمان انجام گرفت.
روش‌کار: در این کارآزمایی بالینی سه‌سوکور شاهددار تصادفی شده که در سال 1403-1402 در بیمارستان‌های وابسته به دانشگاه علوم پزشکی شهید بهشتی انجام شد، 70 نفر از مادران زایمان کرده به دو گروه مداخله و کنترل تقسیم شدند. در طی 24 ساعت نخست، هر 8 ساعت، به گروه مداخله کپسول مفنامیک اسید 250 میلی‌گرمی خوراکی و کپسول 500 میلی‌گرمی حاوی گیاه سنبل­ الطیب و به گروه کنترل کپسول پلاسبو و کپسول مفنامیک اسید 250 میلی‌گرمی خوراکی داده شد. شدت درد پس ­درد زایمان با ابزار VAS نیم ساعت، 1 ساعت و 2 ساعت پس از هر نوبت مداخله ثبت شد. تجزیه و تحلیل داده­ ها با استفاده از نرم‌افزار آماری SPSS (نسخه 21) و آزمون­ های آماری کای دو، دقیق فیشر، تی مستقل و تحلیل رگرسیون انجام شد. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته ­ها: دو گروه مداخله و کنترل از نظر ویژگی‌های دموگرافیک و مامایی قبل از شروع مطالعه اختلاف آماری معناداری نداشتند (05/0<p). بین میانگین نمره درد در دو گروه مداخله و کنترل در طول زمان اختلاف معناداری وجود داشت (001/0>p). همچنین بر اساس نتایج تحلیل واریانس اندازه‌گیری­های مکرر، به‌طور کلی بین میانگین نمره درد درون‌گروهی در طول زمان، در گروه مداخله (001/0>p) کاهش معناداری وجود داشت.
نتیجه­ گیری: ﻧﺘﺎﯾﺞ مصرف کپسول سنبل ­الطیب همراه مفنامیک اسید در کاهش شدت درد پس از زایمان مؤثر واقع شد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The effect of Valeriana officinalis capsule on the severity of postpartum pain: A randomized clinical trial

نویسندگان [English]

  • Atena Mohammadi Rouzbahani 1
  • Fatemeh Asadi 2
  • Kimia Hosseinpour 3
  • Zahra Shirzadi 3
  • Zahra Agha Hossein Shirazi 3
  • Farima Mohamadi 4
  • Mahrokh Dolatian 5
1 M.Sc. of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 M.Sc. of Midwifery, Department of Midwifery, Karaj Branch, Islamic Azad University, Karaj, Iran.
3 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 M.Sc. of Health and Social Welfare, Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
چکیده [English]

Introduction: Postpartum pain is caused by intermittent uterine contractions after placenta and membranes abruption. Due to the harmful effects of chemical drugs, mothers have turned to herbal remedies. The present study was conducted with aim to evaluate the effect of the capsule containing Valeriana officinalis on the severity of postpartum pain.
Methods: This triple-blind randomized controlled clinical trial was conducted in 2023-2024 at hospitals affiliated with Shahid Beheshti University of Medical Sciences. A total of 70 postpartum mothers were divided into two intervention and control groups. During the first 24 hours, every 8 hours, the intervention group was given 250 mg oral mefenamic acid capsules and 500 mg oral valerian capsules, and the control group was given placebo capsules and 250 mg oral mefenamic acid capsules. The intensity of postpartum pain was recorded with the VAS tool half an hour, one hour, and two hours after each intervention. The data were analyzed using SPSS software (version 21) and chi-square, Fisher's exact test, independent t-test, and regression analysis. P<0.05 was considered significant.
Results: There was no statistically significant difference between the intervention and control groups in terms of demographic and obstetric characteristics before the intervention (p>0.05). There was a significant difference between the intervention and control groups in the mean pain score over time (p<0.001). Also, based on the results of the analysis of variance of repeated measurements, there was a significant decrease in the mean intra-group pain score over time in the intervention group (p<0.001).
Conclusion: The use of valerian officinalis capsules along with mefenamic acid was effective in reducing the severity of postpartum pain.

کلیدواژه‌ها [English]

  • Placebo
  • Postpartum pain
  • Valeriana officinalis

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مجله زنان، مامایی و نازایی ایران
دوره 28، شماره 1
فروردین 1404
صفحه 44-57

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