Document Type : Review Article
Authors
1
M.Sc. in Epidemiology, Student Research Community, School of Public Health, Ilam University of Medical Sciences, Ilam, Iran.
2
Associate Professor, Department of Biostatistics, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
3
Professor, Department of Clinical Epidemiology, Social-Psychological Prevention Research Center, of Clinical Epidemiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
4
M.Sc. in Biochemistry, Student Research Community, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Abstract
Introduction: Breast cancer is the most common malignancy in women which causes 19% of annual deaths of women in the world. Estimation of survival rate in patients with this cancer can be used as an important indicator of disease control and evaluation of the treatment methods. Breast cancer survival rates in the country have been reported sporadically and comprehensive information is not available. Therefore, this study was performed with aim to evaluate one to ten-years survival of breast cancer in women by meta-analysis.
Methods: This is a Systematic Review and Meta-analysis study about one to ten-year survival of breast cancer in Iranian women. To do this, the databases including Medlib, Google Scholar, Pubmed, ISI, Science direct, SID, Medline, Magiran, and Irandoc were searched by two trained researchers independently and the articles through key terms and combinations were extracted up to 2013. Data was analyzed by a random effects model meta-analysis, Meta-regression and Cochran test using STATA software (version 11.1) and SPSS software (version 16).
Results: A total of 17 studies with sample size of 11,909 samples were meta-analyzed. 1-year survival rate for breast cancer in Iranian women was 94%, 5-years, 71% and 10-years, 56% and also survival rates of 2, 3 and 4 years were 83%, 79%, 71%, respectively. Minimum and maximum 1-year survival rate was related to the study in Ardebil (82%) and the study in Tehran (99%), respectively.
Discussion: 1 and 5-year survival rate of breast cancer in Iranian women is desirable and survival rate decreases with increasing years passed from the time of diagnosis.
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