مروری بر داروهای گیاهی مؤثر بر گرگرفتگی زنان یائسه

نوع مقاله : مروری

نویسندگان

1 کارشناس ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

2 استاد گروه مامایی و بهداشت باروری، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران.

چکیده

مقدمه: علائم وازوموتور تقریباً در ۷۵% زنان حول‌و‌حوش یائسگی رخ می‌دهند. گرگرفتگی، علت اصلی مراجعه زنان برای دریافت مراقبت دوران یائسگی است. درمان با استروژن مؤثرترین روش موجود برای درمان علائم می‌باشد که با توجه به خطرهای شناخته شده هورمون‌درمانی، بسیاری از زنان به استفاده از داروهای گیاهی برای درمان علائم یائسگی از جمله گرگرفتگی علاقه‌مند هستند، لذا مطالعه حاضر با هدف بررسی کارآزمایی‌های بالینی انجام شده در زمینه بررسی اثربخشی انواع داروهای گیاهی در درمان گرگرفتگی انجام شد.
روش‌کار: در این مطالعه مروری، جهت یافتن مقالات مرتبط پایگاه‌های الکترونیکی SID، Pubmed ،  SCOPUS و Web of Science با استفاده از کلمات کلیدی گرگرفتگی، داروهای گیاهی، زنان یائسه و واژه‌های لاتین Menopause، Herbal medicine، medicine و Hot flash از سال 2019-2002 مورد جستجو قرار گرفتند. مقالاتی که به‌صورت کارآزمایی بالینی صورت گرفته بود، انتخاب شدند.
یافته‌ها: در این مطالعه۳۱ کارآزمایی بالینی تصادفی شناسایی شدند. این مطالعات به بررسی ویتاگنوس (۲)، سویا (4)، کوهوش سیاه (۳)، جینکوبیلوبا (۲)، مریم‌گلی (۴)، سنبل‌الطیب (۲)، تخم کتان (۲)، شبدر قرمز (۵)، گل راعی (۱)، گل مغربی (۲)، شنبلیله (۱) و گل ساعتی (۱) و یک مطالعه نیز که به شکل ترکیبی انجام شده بود، پرداخته بودند. به‌نظر می‌رسد فیتواستروژن‌ها و لیگنان‌های موجود در این گیاهان با کمترین عوارض جانبی، می‌توانند منجر به کاهش شدت و مدت گرگرفتگی شوند.
نتیجه‌گیری:به‌طور ‌کلی، یافته‌های مطالعه حاضر نشان داد که داروهای گیاهی که جزء گروه فیتواستروژن‌ها یا لیگنان‌ها می‌باشند مانند ویتاگنوس، شیرین‌بیان، سویا، شبدر قرمز، بذر کتان، مریم‌گلی، گل ساعتی، سنبل‌الطیب، گل راعی و روغن گل مغربی، می‌توانند به بهبود گرگرفتگی بیانجامند، اما به مطالعات بیشتر در جمعیت بزرگ‌تر نیاز می‌باشد.

کلیدواژه‌ها

عنوان مقاله [English]

A review of the effective herbal medicines on hot flashes in menopausal women

نویسندگان [English]

  • Roghayeh Abdnezhad 1
  • Masoumeh Simbar 2
1 M.Sc. in Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Professor, Department of Midwifery and Reproductive Health, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Science, Tehran, Iran.
چکیده [English]

Introduction: Vasomotor symptoms occur in approximately 75% of menopausal women. Hot flash is the main reason of women's referring to receive menopausal care. Estrogen therapy is the most effective way to treat symptoms; given the known risks of hormone therapy, many women are interested to use herbal medicines for treatment of menopausal symptoms including hot flushes. Therefore, this study was performed with aim to evaluate the clinical trials conducted to evaluate the effectiveness of herbal medicines for treatment of hot flashes.
Methods: In this review study, to find the related articles, the databases of SID, Pubmed, Scopus and Web of Science were searched using the keywords of Menopause, Herbal medicine, medicine and Hot flash from 2002-2019. The articles which were performed as clinical trial were selected.
Results: 31 randomized clinical trials were identified. These studies had investigated Vitagnus (2), soybean (4), Black cohosh (3), Ginkgo biloba (2), sage (4), Valerian (2), Flaxseed (2), red clover (5), Hypericum perforatum (1), evening primrose (2), fenugreek (1) and passion flower (1), and one study was also done as combination. It seems that phytoestrogens and lignans found in these plants can reduce the severity and duration of hot flashes with minimal side effects.
Conclusion: Overall, the findings of this study showed that herbal medicine which belongs to phytoestrogens or lignans like as Vitagnus, licorice, soy, red clover, flax seeds, sage, passion flower, valerian, Hypericum and evening primrose can lead to improvement of hot flashes, but further studies in larger populations are needed.      

کلیدواژه‌ها [English]

  • Complementary medicine
  • Herbal medicine
  • Hot flashes
  • Menopausal women

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مجله زنان، مامایی و نازایی ایران
دوره 23، شماره 8
آبان 1399
صفحه 107-119

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