The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

Effect of K-K9 point acupressure and quince and ginger syrup on nausea and vomiting of pregnancy: A clinical trial

Document Type : Original Article

Authors
Atefeh Abdolhoseini 1
Fatemeh Kameli 2
Maryam Moradi 3
Fatemeh Haghparast 1
Danial Sharifinia 1
Azamsadat Mahmoudian 4
Mobina Abedinpoor 1
Parisa Koshki 1
Fatemeh Afshari 5
1 Nursing Student, Nursing Research Center, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran.
2 Instructor, Department of Community Health Nursing, Nursing Research Center, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran.
3 M.Sc. of Nursing, Nursing Research Center, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran.
4 Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.
5 Instructor, Department of Medical Surgical Nursing, Nursing Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
10.22038/ijogi.2025.74512.5830
Abstract
Introduction: Nausea and vomiting are among the common problems during pregnancy. Given the significant impact of pregnancy-related nausea and vomiting on personal and social lives of pregnant women, the present study was conducted with aim to evaluate and compare the effects of quince and ginger herbal syrup and acupressure at the K-K9 point on nausea and vomiting of pregnancy.
Methods: This single-blind randomized clinical trial study was conducted in 2022 on 44 pregnant women in Gonabad. Participants were randomly assigned into two groups of quince and ginger syrup and acupressure massage at the K-K9 point. In both groups, the 24-hour Pregnancy-Unique Quantification of Emesis and Nausea (PUQE-24) questionnaire was completed for three consecutive days before the intervention. Then, the intervention was carried out for four days. After the end of the intervention, the severity of nausea and vomiting was reassessed in both groups. Data were analyzed using SPSS software (version 22) and Chi-square, One-way ANOVA, and Kruskal-Wallis tests. P<0.05 was considered statistically significant.
Results: The mean score of nausea and vomitting was not significantly different between the two groups before the intervention (p=0.7), but the mean score of nausea and vomitting after the intervention was significantly lower in the quince and ginger group than the K-K9 group (p=0.03).
Conclusion: In this study, quince and ginger syrup and K-K9 acupressure were effective in reducing nausea and vomiting of pregnancy, but quince and ginger syrup had a greater effect on reducing nausea and vomiting of pregnancy, so both methods are recommended to reduce nausea and vomiting of pregnancy.
Keywords
Ginger
K-K9 point
Nausea and vomiting
Pregnancy
Quince
Subjects
  1. Abdolhosseini S, Mokaberinejad R, Aliasl J, Aliasl F. Medicinal plants proposed for nausea and vomiting of pregnancy: a review study based on Iranian traditional medicine. The Iranian Journal of Obstetrics, Gynecology and Infertility 2017; 20(supplement):1-8.
  2. Shourgashti Z, Jafari B, Hosseini H, Emami Moghadam Z. Investigating the Relationship between Stress, Anxiety and Depression with Nausea and Vomiting during Pregnancy (Descriptive study). Navid No 2022; 25(83):39-48.
  3. Saeedi Z, Alidoosti K, Mirzaee F, Ahmadi A, Dahesh T. The effect of combination of psychological counseling and acupressure training with couple therapy approach on nausea and vomiting in pregnancy. The Iranian Journal of Obstetrics, Gynecology and Infertility 2019; 21(11):71-9.
  4. Jarineshin H, Sadeghi SE, Malekshoar M, Sanie Jahromi MS, Rahmanian F, Hatami N, et al. Non-pharmacological methods of controlling nausea and vomiting during pregnancy in Iran: A narrative review study. The Iranian Journal of Obstetrics, Gynecology and Infertility 2022; 24(12):110-23.
  5. Khan A, Ahmad F, Bibi M, Khan I, Said S. Frequency of urinary tract infection in children with nephrotic syndrome. The Professional Medical Journal 2023; 30(05):604-10.
  6. Davis M. Nausea and vomiting of pregnancy: an evidence-based review. The Journal of perinatal & neonatal nursing 2004; 18(4):312-28.
  7. Kheiri Gharibvand S, Javad Nouri M, Mousavi P, Haghighizadeh MH. The effect of ondansetron and K-K9 Acupressure with ondansetron in treatment of nausea and vomiting of pregnancy. The Iranian Journal of Obstetrics, Gynecology and Infertility 2021; 24(9):50-7.
  8. Moradi M, Jalili F, Basiri-Moghadam M, Basiri-Moghadam K. Comparing the Effect of Aromatherapy with Lavender and Rose Essential Oils on the Prevention of Headache Induced by Infusion of Nitroglycerin in Cardiac Care Unit. Journal of Isfahan Medical School 2022; 40(670):300-60.
  9. Tabatabaee A, Behnamrad T. The effect of Complementary on anxiety and quality of life of patients with cancer: systematic review on Randomized Clinical Trials. Clinical Excellence 2021; 11(2):48-59.
  10. Saberi F, Sadat Z, Abedzadeh-Kalahroudi M, Taebi M. Impact of acupressure on nausea and vomiting during pregnancy. Feyz Medical Sciences Journal 2012; 16(3):212-8.
  11. Nourani S, Aparnak F, Sadr Nabavi R, Ebrahimzadeh S. Comparison of K-K9 And P6 Points Acupressure on Nausea And Vomiting in the First Half of Pregnancy. Studies in Medical Sciences 2011; 22(4):369-378.
  12. Adib-Hajbaghery M, Etri M, Hosseinian M. The effect of acupressure on the Pericardium 6 point on pain, nausea and vomiting after appendectomy. Complementary Medicine Journal 2012; 2(2):171-82.
  13. Kalantari Meybodi MS. Investigating the nutritional and medicinal properties of Cydonia oblonga Mill in the diet of patients with non-communicable diseases: A review study. Journal of Preventive Medicine 2020; 7(1):63-72.
  14. Kajkolah M, Mousavi F, Asgari A, Asadi A, Abdolmaleki A. Evaluation of Neuropharmacological Effects of Ginger: A Narrative Review. The Neuroscience Journal of Shefaye Khatam 2022; 10(3):113-22.
  15. Lu C, Chen X, Yan X, He J, Nie Z. The preventive and relieving effects of ginger on postoperative nausea and vomiting: a systematic review and meta-analysis of randomized controlled trials. International journal of nursing studies 2022; 125:104094.
  16. Sabet B, Salkhordeh H, Hedayati Khalil M, Mahboobi M, Babajani S. A review of the ginger products use in reducing pregnancy nausea and vomiting. Paramedical Sciences and Military Health 2017; 11(4):50-6.
  17. Jafari-Dehkordi E, Hashem-Dabaghian F, Aliasl F, Aliasl J, Taghavi-Shirazi M, Sadeghpour O, et al. Comparison of quince with vitamin B6 for treatment of nausea and vomiting in pregnancy: a randomised clinical trial. Journal of Obstetrics and Gynaecology 2017; 37(8):1048-52.
  18. Hosseinkhani S, Sadeghi T. The effect of ginger on pregnancy-induced nausea during first trimester. Iran Journal of Nursing 2009; 22(60):75-83.
  19. Koren G, Boskovic R, Hard M, Maltepe C, Navioz Y, Einarson A. Motherisk—PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancy. American journal of obstetrics and gynecology 2002; 186(5):S228-31.
  20. Jadidi Z, Kazemi F, Shayan A, Aghababaei S. The effect of Benson relaxation training on the severity of nausea and vomiting in pregnant women. The Iranian Journal of Obstetrics, Gynecology and Infertility 2021; 24(8):75-83.
  21. Ozgoli G, Gharayagh Zandi M, Nazem Ekbatani N, Allavi H, Moattar F. Cardamom powder effect on nausea and vomiting during pregnancy. Complement Med J 2015; 14:1056-76.
  22. Narenji F, Delavar M, Rafiei M. Comparison the effects of the ginger fresh root and vitamin B6 on the nausea and vomiting in pregnancy. The Iranian Journal of Obstetrics, Gynecology and Infertility 2012; 15(2):35-41.
  23. Nazari S, Nazari S, Shayan A, Shobeiri F, Ahmadi Nia Tabesh R. Comparison of the Effects of Ondansetron, Vitamin B6 and Ginger Rhizome in Nausea and Vomiting of Pregnancy: A randomized clinical trial. The Iranian Journal of Obstetrics, Gynecology and Infertility 2018; 21(7):29-35.
  24. Pakniat H, Memarzadeh MR, Azh N, Mafi M, Ranjkesh F. Comparison of the effect of chamomile, Ginger and vitamin B6 on treatment of nausea and vomiting in pregnancy: a randomized clinical trial. The Iranian Journal of Obstetrics, Gynecology and Infertility 2018; 21(8):47-54.
  25. Firouzbakht M, Nikpour M, Omidvar S, Kiapour A. Comparative study of effects of ginger with vit. B6 in treatment nausea and vomiting during pregnancy 2013; 8-13.
  26. Küçük E, Bülbül T. The effects of acupressure on nausea, vomiting, and vital signs in patients undergoing gynecologic surgery: a randomized controlled trial. Journal of PeriAnesthesia Nursing 2021; 36(4):420-7.
  27. Shayan A, Nazari S, Nazari S, Ahmadinia H, Rahnavardi M, Shobeiri F, et al. Comparison of the Effect of Jalinus Syrup and Ondansetron Syrup on Nausea and Vomiting during Pregnancy in Pregnant Women: Randomized Clinical Trial. Current Women's Health Reviews 2023; 19(4):155-61.
  28. Saberi F, Sadat Z, Abedzadeh-Kalahroudi M, Taebi M. Acupressure and ginger to relieve nausea and vomiting in pregnancy: a randomized study. Iranian Red Crescent Medical Journal 2013; 15(9):854.
The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 28, Issue 2
April 2025
Pages 59-69