The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

A systematic review on the effects of monosodium glutamate on quantity, concentration, morphology, and motility of sperm in male rats

Document Type : Review Article

Authors
Aref Adeli Mosabbeb 1
Ghazaleh Eslamian 2
Fatemeh Habibollahi 1
Kiana Hasibi 1
Sepehr Khoshbaf Khiabanian 1
Bentolhosna Dehghan nayeri 1
1 M.Sc. Student of Food Sciences and Industry, Student Research Committee, School of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Assistant Professor, Department of Cellular and Molecular Nutrition, School of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
10.22038/ijogi.2024.80938.6131
Abstract
Introduction: Male infertility is a significant global issue affecting men's health, characterized by dysfunction or suboptimal performance of components of the male reproductive system. Types of nutrition can affect positively or negatively on fertility and this effect depends on the quality and quantity of food intake. The present systematic review was conducted with aim to investigate the effects of monosodium glutamate consumption on sperm quantity, concentration, morphology, and motility in male rats.
Methods: In this systematic review, search was conducted on English and Persian databases of Medline, Embase, Google Scholar, Web of Science, Science Direct, Scopus, Magiran, SID, ISC, and Cochrane from January 2010 to May 2023 with the keywords related to male infertility, monosodium glutamate, male rats, sperm count, live sperm, sperm morphology, and sperm motility.
Results: Fourteen studies were included in this systematic review. The findings indicated that monosodium glutamate consumption was associated with decreased sperm count, live sperm percentage, and alterations in sperm morphology in male rats. Most studies reported a decrease in sperm motility with monosodium glutamate intake, although some studies observed an increase in sperm motility.
Conclusion: Increased consumption of monosodium glutamate is linked to reductions in sperm quantity, concentration, and motility in male rats, potentially contributing to elevated infertility rates. Therefore, prolonged and high-dose consumption of monosodium glutamate may significantly impact sperm characteristics.
Keywords
Male infertility
Male rats
Monosodium glutamate
Sperm
Subjects
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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 27, Issue 7
September 2024
Pages 67-81