The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

Effect of combined exercises (aerobic-pilates) on the serum level of interleukin 10 and blood platelets in women with breast cancer

Document Type : Original Article

Authors
Bohlool Ghorbanian 1
Vahid Montazeri 2
Fahimeh Rostami 3
Tohid Khanvari 4
1 Associate Professor, Department of Exercise Sciences, School of Education Sciences and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran.
2 Associate Professor, Department of Exercise Sciences, School of Medical Science, Tabriz University of Medical Science, Tabriz, Iran.
3 M.Sc. of Exercise Physiology, School of Education Sciences and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran.
4 Ph.D. Student of Exercise Physiology, School of Education Sciences and Psychology, Tabriz University of Medical Science, Tabriz, Iran.
10.22038/ijogi.2021.17988
Abstract
Introduction:Exercise can play a supportive role in the improvement of breast cancer by regulating and modulating cytokines. Interleukin 10 is an anti-inflammatory and anti-tumor cytokine that plays an important role in inhibiting tumor growth. This study was performed with aim to evaluate the effect of 12 weeks of combined exercise (aerobic_pilates) on the serum level of interleukin 10 and blood platelets in women with breast cancer.
Methods: This experimental study was performed on 30 women with breast cancer who had undergone at least 6 months of surgery and had received chemotherapy and were under treatment with medication in Azarbaijan Shahid Madani University in 2019. The subjects were divided into experimental and control groups. The experimental group performed 3 sessions of exercise each week (aerobic-pilates) for 12 weeks. During this time, the control group did not participate in any exercise or physical activity program. Blood samples were obtained before and 48 hours after exercise intervention to extract the variables. Data were analyzed by SPSS software (version 20) and independent and correlated t-test. P<0.05 was considered statistically significant.
Results: The results of correlated t-test showed that the serum level of interleukin 10 (P =0.001) and the number of blood platelets (P =0.041) significantly increased in the experimental group after 12 weeks of combined training (aerobic-Pilates) compared to the pre-test, while this change was not significant in the control group (p> 0.05).
Conclusion: Performing combined exercises (aerobic_Pilates) by improving the status of interleukin 10 as an anti-inflammatory and anti-tumor cytokine can be useful in improving the health status of women with breast cancer. Therefore, designing and performing such exercises in this population can solve many problems of these loved ones.
Keywords
Blood platelet
Breast cancer
Combined exercise
Interleukin 10
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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 24, Issue 1
March 2021
Pages 9-17