The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

Comparison of the effect of trigger of ovulation with HCG and HCG plus oxytocin on the biochemical pregnancy

Document Type : Original Article

Authors
Shahnaz Nezamdoust 1
Farahnaz Farzaneh 2
1 Resident, Department of Obstetrics and Gynecology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan Iran.
2 Associate professor, Department of Obstetrics and Gynecology, Fellowship of Infertility, Infectious Diseases and Tropical Medicine Research Center, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
10.22038/ijogi.2020.15549
Abstract
Introduction: Infertility is defined as not getting pregnant after 1 year of unprotected intercourse. Given the large area and high population of Sistan & Baluchestan province and many patients referring to the infertility center of Ali-ibn-e Abitaleb Hospital, this study was performed with aim to compare two methods of ovulation triggers for treatment of infertility in women with no ovulation.
Methods: This clinical trial was conducted on 100 infertile women (50 in each group) with infertility referring to gynecology clinic of Ali ibn-e Abitaleb Hospital of Zahedan  in 2017-2018. Patients were randomly assigned into two groups of HCG or HCG plus Oxytocin groups. The rate of pregnancy was evaluated. Data were analyzed by SPSS software (version 22) and Chi-square, independent t and Mann-Whitney test. PResults: According to the results of Chi-square test, frequency of pregnancy was significantly higher in HCG plus oxytocin group than HCG alone group (p=0.016).
Conclusion: HCG plus oxytocin significantly increases pregnancy rate in infertile women.
Keywords
HCG
Induction Ovulation
IUI
Oxytocin
Pregnancy rate
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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 22, Issue 12
February 2020
Pages 19-23