The Iranian Journal of Obstetrics, Gynecology and Infertility

The Iranian Journal of Obstetrics, Gynecology and Infertility

Hydatidiform molar pregnancy presenting with preeclampsia in 6th weeks of pregnancy: a case report

Document Type : Review Article

Authors
Laya Shirinzadeh 1
Zohreh Yousefi 2
Amir Hossain Jafarian 2
Behrouz Davachi 3
Leila Mousavi Seresht 4
Nooshin Babapour 4
Anis Darvish 5
1 Fellowship of Gynecology Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Professor, Department of Obstetrics and Gynecology, Fellowship of Gynecology Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Associate professor, Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Resident Fellowship of Gynecology Oncology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
5 Resident, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
10.22038/ijogi.2018.11802
Abstract
Introduction: preeclampsia is one of the rare symptoms of molar pregnancy and is more prevalent in pregnancies with large volumes of abnormal trophoblastic tissue. Preeclampsia is associated with hypertension and proteinuria and rarely occurs in patients with Hydatidiform mole. Since in most cases, molar pregnancy is diagnosed by sonography at first trimester of pregnancy, the possibility of gestational trophoblastic disease should be considered in all patients with preeclampsia in first trimester of pregnancy. The aim of this report is to introduce a case of hydatidiform molar pregnancy with preeclampsia in 6th weeks of pregnancy.
Case report: A 15-year-old primigravid female with 6 weeks of menstrual retardation and diagnosis of molar pregnancy with increase of β-HCG titers, proteinuria and upper extremity edema was referred to emergency of maternity ward of an academic hospital, Mashhad University of Medical Sciences in 2017. Preeclampsia was confirmed. After curettage, hydatidiform mole was diagnosed. Preeclampsia associated with molar pregnancy was diagnosed. After mole curettage, blood pressure reached to normal and edema and other symptoms were gradually improved.
Conclusion: Preeclampsia is one of the rare symptoms in molar pregnancy. Considering that in most cases molar pregnancy is diagnosed with ultrasound in the first trimester of pregnancy, it is recommended that hydatidiform mole should be considered in all patients with preeclampsia in early pregnancy.
Keywords
First trimester of pregnancy
Hydatidiform mole
Preeclampsia
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The Iranian Journal of Obstetrics, Gynecology and Infertility
Volume 21, Issue 7
September 2018
Pages 97-100