نقش ویتامین D در سلامت باروری زنان و مردان: یک مطالعه مروری

نوع مقاله : مروری

نویسندگان

1 دانشجوی دکترای تخصصی بهداشت باروری، کمیته تحقیقات دانشجویی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 دانشیار گروه مامایی، مرکز تحقیقات مراقبت مبتنی بر شواهد، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 کارشناس مامایی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: کمبود ویتامین Dدر سنین باروری امری شایع است. مطالعات اخیر نشان می­دهد که کمبود ویتامین Dبا کارکردهای ضعیف تولید‌مثل در زنان و مردان سنین باروری همراه است. لذا مطالعه حاضر با هدف تعیین نقش ویتامین D بر برخی عملکردهای تولید مثلی انسان (مانند سندرم تخمدان پلی‌کیستیک، آندومتریوز، میوم، نارسایی زودرس تخمدان‌ها، ناباروری مردان و IVF) انجام شد.
روش‌کار: در این مطالعه مروری، مطالعات انجام شده فارسی و انگلیسی در طی سال‌های 1378 تا آبان ماه 1395، با استفاده از کلید واژه‌های فارسی ویتامین D، باروری، ناباروری و کلید واژه‌های انگلیسی fertility، infertility، vitamin D، در پایگاه‌های اطلاعاتی معتبر SID، Iranmedx، Scopus، Irandoc، PubMed، Magiran و Google scholar جستجو شدند.
یافته‌ها: 35 مقاله استخراج شده از 302 مطالعه در ارتباط با نقش ویتامین D در عملکرد تولید مثلی انسان مورد بررسی قرار گرفت. نتایج حاصل از آخرین مطالعات انجام شده دراین زمینه مورد بحث قرار گرفت و خلاصه شد.
نتیجه­گیری: کمبود ویتامین Dکه به عنوان سطح سرمی کمتر از 20 نانوگرم در میلی‌لیتر در نظر گرفته می‌شود، در سنین باروری شایع است و کمبود ویتامین D در عملکردهای تولید مثل مانند سندرم تخمدان پلی‌کیستیک، فیبروم رحمی، پارامترهای نامناسب اسپرم و در شکست درمان IVF نقش دارد، بنابراین مکمل ویتامین Dدر درمان ناباروری زنان و مردان توصیه می‌شود.

کلیدواژه‌ها

عنوان مقاله [English]

The Role of Vitamin D in Male and Female Reproductive Health: A Review Study

نویسندگان [English]

  • Morvarid Irani 1
  • Khadijeh Mirzaei 2
  • Nahid Maleki 1
  • Ensieh Entezari 3
1 1. Research Committee, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
2 Associate Professor, Department of Midwifery, Evidence-based Care Research Center, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
3 BC of Midwifery, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: Vitamin D deficiency is common during reproductive age. Recent data suggest that vitamin D deficiency is associated with poor reproductive function in women and men. Therefore, this study was performed with aim to determine the role of vitamin D on some reproductive function (such as polycystic ovary syndrome, endometriosis, myoma, premature ovary failure, male infertility, and in vitro fertilization (IVF).
Methods: In this review study, Persian and English articles that published during 1997 to 2016 with keywords of vitamin D, infertility, fertility were searched in PubMed, Magiran, Google Scholar, Iranmedex, Scopus, Irandoc and SID databases.
Results: A total of 35 studies which were extracted from 302 articles related to the role of vitamin D on some reproductive function were studied. The results of latest research articles in this field were discussed and summarized.
Conclusion: Deficiency of vitamin D defined as serum concentration of <20 ng/ml is common in reproductive age. Vitamin D deficiency has a role in reproductive dysfunction, such as polycystic ovary syndrome, uterine fibroids, abnormal semen parameters and in IVF failure. So, vitamin D supplementation is advised in infertility therapy in both male and female.

کلیدواژه‌ها [English]

  • Assisted reproductive techniques
  • Endometriosis infertility
  • Infertility
  • in vitro fertilization
  • Male Infertility
  • Myoma infertility
  • Premature ovary failure
  • Polycystic ovary syndrome
  • Vitamin D

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مجله زنان، مامایی و نازایی ایران
دوره 20، شماره 3
خرداد 1396
صفحه 98-109

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