تأثیر تمرینات مقاومتی همراه با مصرف کلسیم بر سطح هورمون آنتی مولرین و برخی از شاخص‌های متابولیکی مبتلایان به سندرم تخمدان پلی کیستیک

نویسندگان

1 دانشیار گروه فیزیولوژی ورزشی، دانشکده علوم انسانی، دانشگاه اراک، اراک، ایران.

2 کارشناس ارشد فیزیولوژی ورزشی، دانشکده علوم انسانی، دانشگاه اراک، اراک، ایران.

چکیده

مقدمه: سندرم تخمدان پلی‌کیستیک یکی از متداول‌ترین اختلالات هورمونی در زنان سنین باروری است. در بسیاری از موارد این بیماری با ناباروری و خطر افزایش سندرم متابولیک همراه است. مطالعه حاضر با هدف بررسی تأثیر هشت هفته تمرین مقاومتی و مکمل کلسیم بر سطح سرمی هورمون آنتی مولرین و شاخص‌های متابولیکی در زنان مبتلا به PCOS انجام شد.
 روش‌کار: این مطالعه نیمهتجربی با طرح پیش آزمون- پس آزمون بر روی 30 زن مبتلا به PCOS که در سال 1393 به یکی ازمراکز درمانی بیماری‌های زنان شهر اراک مراجعه کرده بودند، انجام شد. افراد به طور تصادفی به سه گروه 10 نفره تمرین مقاومتی و دارونما، تمرین مقاومتی و مصرف مکمل کلسیم (1000 میلی گرم در روز) و کنترل تقسیم شدند. برنامه تمرین مقاومتی شامل سه جلسه در هفته و برای مدت 8 هفته بود و هر جلسه تمرین شامل 1 تا 2 نوبت 5 تا 20 تکراری با شدت 40 تا 60 درصد یک تکرار بیشینه بود. سطوح سرمی هورمون آنتی‌مولرین و شاخص‌های متابولیکی، قبل و بعد از دوره تمرین ارزیابی شد. داده‌ها با استفاده از نرم افزار آماری SPSS (نسخه 18) و آزمون‌های تحلیل واریانس دو طرفه و تحلیل کوواریانس تجزیه و تحلیل شدند. میزان p کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: بعد از 8 هفته تمرین مقاومتی کلسترول ‌تام، تری‌گلسیرید، LDL-c و شاخص مقاومت به انسولین به طور معنی‌دار کاهش یافت (05/0p<). تحلیل داده‌ها نشان داد که مکمل دهی کلسیم همراه با تمرین مقاومتی منجر به بهبود بیشتر در شاخص‌های متابولیکی و سطح سرمی AMH می‌شود (05/0p<).
نتیجه‌گیری: تمرین مقاومتی به همراه مکمل کلسیم در طی دو ماه می‌تواند اثرات مطلوبی بر شاخص‌های متابولیکی و ذخیره تخمدانی در زنان مبتلا به PCOS داشته باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of resistance exercises with calcium consumption on level of anti-mullerian hormone and some metabolic indices in women with polycystic ovarian syndrome

نویسندگان [English]

  • Abbas Saremi 1
  • Mohadaseh Sadat Yaghoubi 2
1 Associate Professor, Department of Exercise Physiology, School of Humanities Sciences, Arak University, Arak, Iran.
2 M.Sc. in Exercise Physiology, Faculty School of Humanities Sciences, Arak University, Arak, Iran.
چکیده [English]

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrinal disorders in women at reproductive age. In many cases, PCOS is associated with infertility and increased risk of metabolic syndrome. This study was performed with aim to investigate the effect of 8-week resistance exercise and calcium supplementation on anti-mullerian hormone (AMH) level and metabolic parameters in women with PCOS.
Methods: This semi-experimental study was performed with pretest–posttest design on 30 women with PCOS who were referred to one of the medical centers of Arak in 2014. They were randomly assigned to three groups of resistance exercise and placebo, resistance exercise and calcium supplementation consumption (1000 mg/d), and control with 10 cases in each group. The protocol consisted of 3 sessions per week of exercise for 8 weeks, each session including 1-2 sets of 5–20 repetitions at 40–60% of 1RM(one repetition maximum). Serum levels of AMH and metabolic parameters were assessed before and after the training period. Data were analyzed using SPSS software (version 18), and two-way ANOVA and ANCOVA tests.  PResults: After 8 week total cholesterol resistance exercise, LDL-c, triglycerides and insulin resistance index were significantly decreased (P<0.05). Data analysis showed that calcium supplementation in conjunction with resistance exercise leads to more improvement in metabolic indices and serum level of AMH (P<0.05).
Conclusion: Resistance training in conjunction with calcium supplementation for two months can have beneficial effects on metabolic indices and ovarian reserve in women with PCOS.

کلیدواژه‌ها [English]

  • Anti-mullerian hormone
  • Calcium
  • Metabolic indices
  • Polycystic ovary syndrome
  • Resistance exercise
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