تأثیر تمرین تناوبی شدید و مصرف گل گاوزبان بر پروتئین واکنشگر C و فریتین سرم زنان دارای اضافه وزن و چاق

نوع مقاله: اصیل پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی، واحد اصفهان (خوراسگان)، اصفهان، ایران.

2 دانشیار گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه آزاد اسلامی، واحد اصفهان (خوراسگان)، اصفهان، ایران.

چکیده

مقدمه: طی چاقی، نشانگرهای التهابی از جمله فریتین و پروتئین واکنشگر C افزایش می‌یابد که سازوکار اصلی تصلب شرایین و مقاومت به انسولین است. فعالیت منظم ورزشی و دارو می‌تواند باعث کاهش این عوامل شده و خطر ابتلاء به بیماری‌های مزمن را کاهش دهد. لذا مطالعه حاضر با هدف مقایسه تأثیر 12 هفته تمرین تناوبی با شدت بالا (HIIT) و مصرف گل گاوزبان بر سطوح سرمی CRP و فریتین زنان دارای اضافه وزن و چاق انجام شد.
روش‌کار: این مطالعه‏ کارآزمایی بالینی تصادفی شده در سال 1397 بر روی 40 زن دارای اضافه وزن و چاق انجام شد. افراد به‌صورت تصادفی در 4 گروه 10 نفری (تمرین- مکمل، تمرین، مکمل و کنترل) قرار گرفتند. نمونه‌گیری‏های خونی قبل و پس از 12 هفته برای اندازه‌گیری سطوح CRP و فریتین جمع‌آوری و آنالیز شد. برنامه تمرینی با شدت بالا (95-85% ضربان قلب بیشینه) 3 جلسه در هفته به‌مدت 12 هفته انجام و گروه‏هایی که از گل گاوزبان استفاده می‌کردند، هر روز به‌میزان 4 ‏گرم گل گاوزبان را به‌صورت دم‏کرده به‌مدت 12 هفته دریافت کردند. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 21) و آزمون‏های تحلیل کوواریانس، تی زوجی، شاپیروویلک و لوین انجام شد. میزان p کمتر از 05/0 معنادار در نظر گرفته شد.
یافته‌ها: پس از 12 هفته تمرین تناوبی شدید، سطح سرمی فریتین بعد از مداخله نسبت به قبل از مداخله افزایش یافت؛ به‌طوری‌که این افزایش در گروه تمرین (033/0=p) و گروه گل گاوزبان (016/0=p) معنادار بود، اما در گروه تمرین-گل گاوزبان (323/0=p) و گروه کنترل (612/0=p) معنادار نبود. همچنین میزان CRP بعد از مداخله نسبت به قبل از مداخله کاهش یافت؛ به‌طوری‌که این کاهش در گروه تمرین (05/0=p) و گروه گل گاوزبان (001/0=p) معنادار بود، اما در گروه تمرین - گل گاوزبان (196/0=p) و گروه کنترل (571/0=p) معنادار نبود.
نتیجه‌گیری: انجام تمرین تناوبی شدید به‌همراه مصرف مکمل گل گاوزبان به‌واسطه کاهش CRP و افزایش سطح سرمی فریتین می‌تواند در بهبود عوارض و بیماری‌های ناشی از چاقی مفید باشد. همچنین توانسته بر چاقی عمومی تأثیر داشته باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of high intensity interval training and use of Echium amoenum on serum ferritin and CRP levels in overweight and obese women

نویسندگان [English]

  • Maryam Nasri 1
  • Farzaneh Taghian 2
1 M.Sc. of Sport Physiology, School of Physical Education and Sport Science, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.
2 Associate professor, Department of Sport Physiology, School of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.
چکیده [English]

Introduction: During obesity, inflammatory markers such as ferritin and C-reactive protein are increased, which is a major mechanism of atherosclerosis and insulin resistance. Regular exercise and medication can reduce these factors and reduce the risk of chronic diseases. This study was performed with aim to compare the effect of 12 weeks of high intensity interval training (HIIT) and use of borage (Echium amoenum L.) on serum CRP and ferritin levels in overweight and obese women.
Methods: This randomized clinical trial study was performed on 40 overweight and obese women in 2018. The subjects were randomly divided into four groups of 10 cases in each group (Exercise-Supplement, Exercise, Supplement and Control). Blood samples were collected and analyzed before and after 12 weeks to measure the levels of CRP and ferritin. A high intensity interval training program (85-95% of maximal heart rate) was performed three times a week for 12 weeks, and groups that used Echium amoenum daily received 4 g dissolved in 250 ml of water, for 12 weeks. Data were analyzed by SPSS software (version 21) and Paired t-test and covariance tests and Shapirowilk and Levin tests. PResults: After 12 weeks HIT training, serum ferritin levels increased after the intervention compared to the pre-intervention, so that this increase was significant in the training group (p=0.033) and Echium amoenum group (p=0.016), but was not significant in the training-Echium amoenum group (p=0.323) and control group (p=0.612). Also, CRP decreased after the intervention compared to the pre-intervention, so that this decrease was significant in the training group (p=0.05) and Echium amoenum group (p=0.001), but was not significant in the training-Echium amoenum group (p=0.196) and control group (p=0.571).
Conclusion: Performing severe intermittent exercise along with use of Echium amoenum supplementation by reducing CRP and increasing serum ferritin level can improve the complications and diseases caused by obesity. It has also had an impact on general obesity.

کلیدواژه‌ها [English]

  • CRP
  • Echium amoenum supplement
  • Ferritins
  • HIT training
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