اثر تمرینات هوازی همراه با مکمل یاری کلرلا بر مقاومت به انسولین و سطح سرمی گرلین زنان چاق

نوع مقاله: اصیل پژوهشی

نویسندگان

1 کارشناس ارشد گروه تربیت بدنی، واحد محلات، دانشگاه آزاد اسلامی، محلات، ایران.

2 دانشیار گروه تربیت بدنی، واحد محلات، دانشگاه آزاد اسلامی، محلات، ایران.

3 استادیار گروه تربیت بدنی، دانشکده ادبیات و علوم انسانی، دانشگاه قم، قم، ایران.

چکیده

مقدمه: چاقی و اضافه وزن با بسیاری از بیماری‌ها ارتباط دارند. اثرات تمرین منظم یا کلرلا نیز هر یک به‌طور مجزا بر کنترل بیماری‌ها تأیید شده است. مطالعه حاضر با هدف بررسی اثر تمرینات هوازی همراه با مکمل یاری کلرلا بر مقاومت به انسولین و سطح سرمی گرلین زنان چاق غیر‌فعال انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی تصادفی دوسوکور در سال 1396 بر روی 32 زن چاق در شهرستان محلات انجام شد. افراد به‌طور تصادفی و مساوی در چهار گروه تمرین، مکمل کلرلا، تمرین+ مکمل و کنترل قرار گرفتند. مداخلات به‌مدت هشت هفته انجام شد. مصرف کلرلا، روزانه چهار عدد به شکل قرص مکمل 300 میلی‌گرمی بود. برنامه تمرینی شامل دویدن روی نوارگردان با 65% ضربان قلب بیشینه به‌مدت 16 دقیقه در هفته اول بود که در هفته هشتم به 30 دقیقه با 80% ضربان قلب بیشینه رسید. دو روز قبل و بعد از پایان مداخلات، به منظور اندازه‌گیری گرلین، گلوکز، انسولین و مقاومت انسولین، از هر چهار گروه در وضعیت 12 ساعت ناشتایی نمونه خونی اخذ گردید. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 16) و آزمون تحلیل واریانس دوطرفه با اندازه‌گیری مکرر انجام شد. میزان p‌ کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: گلوکز، انسولین و مقاومت به انسولین تنها در دو گروه تمرین+کلرلا و تمرین در مقایسه با دو گروه دیگر به‌طور معناداری کاهش یافت (05/0>p)، اما بین دو گروه تفاوت معنی‌دار نبود. میزان و الگوی تغییرات گرلین سرم در چهار گروه تفاوت معناداری نداشت (05/0<p).
نتیجه‌گیری: تمرینات هوازی منجر به کاهش مقاومت به انسولین زنان چاق می‌شود، اما اثر معناداری بر سطح سرمی گرلین ندارد. از طرف دیگر مصرف مکمل کلرلا اثر معناداری را بر هیچ‌کدام از متغیرها نشان نداد و افزودن آن به تمرین هوازی نیز اثر تمرین را بیشتر نکرد.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of aerobic training with Chlorella supplement on insulin resistance and serum ghrelin levels in obese women

نویسندگان [English]

  • Maryam Esmaieli 1
  • Bahram Abedi 2
  • Fazlollah Fathollahi Shoorabeh 3
1 M.Sc. of Physical Education, Islamic Azad University, Mahallat Branch, Mahallat, Iran.
2 Associate Professor, Department of Physical Education, Islamic Azad University, Mahallat Branch, Mahallat, Iran.
3 Assistant Professor, Department of Physical Education, Faculty of Literature and Human Sciences, Qom University, Qom, Iran.
چکیده [English]

Introduction: Obesity and overweight are associated with many diseases. The effects of regular exercises or Chlorella on disease control have been also confirmed individually. The purpose of this study was to investigate the effect of aerobic training with Chlorella supplement on insulin resistance and serum ghrelin level in obese sedentary women.
Materials and Methods: This randomized double-blind clinical trial was conducted on 32 obese women in Mahallat city, Iran, in 2017. The subjects were randomly assigned into four groups of exercise, supplementation with Chlorella, exercise plus supplementation, and control. Interventions were completed for 8 weeks. The daily intake of Chlorella was four 300 mg tablets (1 before breakfast, 2 before lunch, and 1 before dinner). The aerobic exercise program included running on a treadmill for 16 min with a maximum heart rate of 65% in the first week, which reached to 30 min and a maximum heart rate of 80% in the eighth week. Two days before and after the end of the interventions, blood samples were taken from all four groups in order to measure ghrelin, glucose, insulin, and insulin resistance. Data analysis was performed in SPSS software (version 16) using two-way and repeated measurements ANOVA. P-value less than 0.05 was considered significant.
Results: Glucose and insulin levels, as well as insulin resistance were significantly reduced in the exercise plus Chlorella and exercise groups, compared to those in the other two groups (P<0.05). However, the levels and pattern of ghrelin changes were not significantly different among the four groups (P>0.05).
Conclusion: Aerobic exercises lead to the reduction of insulin resistance in obese women, but no significant effect was observed on ghrelin. On the other hand, Chlorella supplementation did not show any significant effect on any of the variables. The use of Chlorella supplement along with aerobic exercise also exerted no effect.

کلیدواژه‌ها [English]

  • insulin resistance
  • aerobic exercise
  • ghrelin
  • chlorella
  • Obesity
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