مقایسه اثر کرم خرفه و لانولین بر درد نوک پستان زنان شیرده: کارآزمایی بالینی تصادفی شده

نوع مقاله: اصیل پژوهشی

نویسندگان

1 دانشجوی کارشناسی ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

2 مربی گروه مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

3 استادیار گروه فارماکولوژی، مرکز تحقیقات فارماکولوژیک و گیاهان دارویی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

4 استاد گروه آمار زیستی و اپیدمیولوژی، مرکز تحقیقات علوم بهداشتی، دانشکده بهداشت، دانشگاه علوم پزشکی مشهد، مشهد، ایران.

چکیده

مقدمه: درد نوک پستان، یکی از شکایات شایع مادران در روزهای اول بعد از زایمان و دومین علت قطع زودهنگام شیردهی می‌باشد. لانولین، درمان توصیه شده جهت بهبود درد نوک پستان است. از طرفی خرفه به دلیل ترکیبات فلاونوئید و ساپونین، دارای اثرات ضد دردی و ضد التهابی ثابت شده‌ای می باشد. لذا مطالعه حاضر با هدف تعیین و مقایسه اثر کرم خرفه با لانولین بر درد نوک پستان در زنان شیرده انجام شد.
روش‌کار: این مطالعه کارآزمایی بالینی تصادفی شده دو سوکور در سال 1395 بر روی 86 زن شیرده مبتلا به درد نوک پستان در شهر مشهد انجام شد. افراد به صورت تصادفی در دو گروه 43 نفری کرم خرفه و لانولین قرار گرفتند. روش صحیح شیردهی و طریقه استعمال دارو به افراد هر دو گروه آموزش داده شد. نمره درد نوک پستان قبل از شروع مداخله و روزهای سوم و هشتم بعد از درمان با استفاده از مقیاس عددی درد توسط پژوهشگر اندازه‌گیری و ثبت شد. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 22) و آزمون‌های آماری تی، فیشر، کای دو و ویلکاکسون انجام شد. میزان p‌ کمتر از 05/0 معنی‌دار در نظر گرفته شد.
یافته‌ها: دو گروه قبل از مداخله از نظر شدت درد همگن بودند. اختلاف معناداری در شدت درد در هر یک از گروه‌ها در روز سوم و هشتم نسبت به قبل مشاهده شد و شدت درد در هر دو گروه کاهش یافته بود (001/0>p). شدت درد بین دو گروه در روز سوم و هشتم اختلاف معناداری داشت؛ به‌طوری‌که شدت درد در گروه خرفه کمتر از گروه لانولین بود (001/0>p).
نتیجه‌گیری: کرم خرفه در بهبود درد نوک پستان مؤثرتر از لانولین می‌باشد.

کلیدواژه‌ها


عنوان مقاله [English]

Comparison of purslane cream and lanolin on nipple pain among breastfeeding women: A randomized clinical trial

نویسندگان [English]

  • Azin Niazi 1
  • Sedigheh Yousefzadeh 2
  • Hasan Rakhshandeh 3
  • Habibollah Esmaeili 4
1 M.Sc. Student of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
2 Instructor, Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Assistant Professor, Department of Pharmacology, Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Professor, Department of Biostatistics and Epidemiology, Medical Sciences Research Center, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]

Introduction: Maternal nipple pain is one of the common complaints on the first few days post birth, which is the second cause of early discontinuation of breastfeeding. Lanolin is the recommended treatment for relieving the nipple pain. In addition, purslane has analgesic and anti-inflammatory effects due to containing flavonoids and saponins. Regarding this, the present study was conducted with the aim of determining the effect of purslane cream and lanolin on nipple pain among the breastfeeding women.
Material and Methods: This double-blind, randomized controlled trial was conducted on 86 breastfeeding women suffering from nipple pain in Mashhad, Iran, in 2016. The samples were randomly assigned into two groups of purslane cream and lanolin (n=43 cases in each group). Both groups were trained about the correct method of breastfeeding and using cream. The nipple pain scores were measured and recorded by the researcher before the treatment, as well as 3 and 8 days post-intervention using the numeric pain scale. Data analysis was performed in SPSS software (version 22) using the t-test, Fisher's exact test, Chi-square test, and Wilcoxon test. P-value less than 0.05 was considered statistically significant.
Results: According to the results, the two groups were comparable before the intervention in terms of pain severity. The two groups showed a significant difference in pain severity on days 3 and 8 post-intervention, compared to the pre-intervention stage; accordingly, the severity of pain was decreased in both groups (P<0.001). Furthermore, there was a significant difference between the two groups regarding the pain severity on the third and eighth days post-intervention (P<0.001). In this regard, the purslane group showed a lower pain severity than the lanolin group.
Conclusion: As the findings of the present study indicated, purslane cream was more effective in the treatment of nipple pain than lanolin.

کلیدواژه‌ها [English]

  • Nipples
  • Purslane
  • Lanolin
  • Breastfeeding
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